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Organic compounds that contain a carboxyl group bonded to an organic functional group; carboxyl groups consist of a carbonyl group bonded to a hydroxy group. Includes compounds that are derived from carboxylic acids.
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Amfenac Sodium Monohydrate (CAS 61618-27-7) is a synthetic non-steroidal anti-inflammatory compound structurally characterized by an acetic acid moiety It functions by inhibiting cyclooxygenase (COX) enzymes consequently suppressing prostaglandin synthesis and mitigating inflammatory processes and pain signaling Amfenac Sodium Monohydrate is utilized in biomedical research to investigate inflammatory pathways and to evaluate non-steroidal analgesic drug effects in cellular and animal models of inflammation Its well-defined inhibitory mechanism makes it a valuable tool for elucidating COX-mediated physiological and pathological responses
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HO-PEG-CH2COOH (MW 35,000) is a carboxy-terminated polyethylene glycol (PEG) polymer used as a hydrophilic spacer for PROTAC synthesis and other bioconjugation applications. The polymer features a hydroxyl terminus and a carboxymethyl terminus, providing a reactive carboxylic acid for coupling chemistries. Supplied as a white to off-white solid with ~95.0% purity; recommended storage is -20°C under nitrogen.
High molecular weight PEG spacer (35,000 Da) for increased solubility and linker length.
Carboxy-terminated for straightforward amide or ester coupling.
Hydroxyl-terminated opposite end for orthogonal functionalization.
Solid powder form is easy to handle and weigh for synthesis workflows.
Stable under recommended storage; in solvent store at -80°C for extended stability.
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ARL67156 trisodium is a small-molecule research inhibitor of ecto-ATPase (NTPDase) enzymes, provided as the trisodium salt in solid form. It is used to study nucleotide hydrolysis and related pathologies such as calcific aortic valve disease and asthma.
Selective inhibitor of NTPDase1 (CD39), NTPDase3, and NPP1.
Reported Ki values approximately 11 μM (NTPDase1), 18 μM (NTPDase3), and 12 μM (NPP1).
High reported purity (99.94%).
Molecular weight about 785.05 g·mol-1 and exact formula C15H21Br2N5Na3O12P3.
Supplied as a solid trisodium salt, available in small research pack sizes.
Store sealed and away from moisture at -20°C; in solution, store at -80°C (up to 6 months) or -20°C (up to 1 month).
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diMal-O-CH2COOH is a cleavable ADC linker. It is for research use only and not intended for human use. This product appears as a solid with a white to off-white color.
Cleavable ADC linker
For research use only
Not intended for human use
Appears as a solid
Color: white to off-white
Molecular weight: 308.24
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Fmoc-NH-PEG1-CH2COOH is an Fmoc-protected PEG1 linker used as a cleavable linker for antibody-drug conjugate (ADC) synthesis and as a PEG-based PROTAC linker. The compound is supplied as a white powder with reported high purity and is available in multiple pack sizes, including a 5 G pack.
Fmoc-protected amine with a PEG1 spacer and terminal carboxylic acid.
Used as a cleavable linker in ADC and PROTAC syntheses.
Supplied as a white powder; multiple pack sizes available.
Reported high purity suitable for research applications.
Chemical identifiers: CAS 260367-12-2; molecular weight 341.36; formula C19H19NO5.
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